Epithelial-mesenchymal plasticity and circulating tumor cells: Travel companions to metastases
Francart, Marie-Emilie, Lambert, Justine, Vanwynsberghe, Aline, Thompson, Rik, Bourcy, Morgane, Polette, Myriam, & Gilles, Christine (2018) Epithelial-mesenchymal plasticity and circulating tumor cells: Travel companions to metastases. Developmental Dynamics, 247(3), pp. 432-450.
41 citations on Web of Science
42 citations on Scopus
DNA methylation profiling of breast cancer cell lines along the epithelial mesenchymal spectrum - implications for the choice of circulating tumour DNA methylation markers
Viet-Phuong Le, Anh, Szaumkessel, Marcin, Tan, Tuan Zea, Thiery, Jean-Paul, Thompson, Erik Walter, & Dobrovic, Alexander (2018) DNA methylation profiling of breast cancer cell lines along the epithelial mesenchymal spectrum - implications for the choice of circulating tumour DNA methylation markers. [Working Paper] (Unpublished)
Targeting epithelial–mesenchymal plasticity in cancer: Clinical and preclinical advances in therapy and monitoring
Bhatia, Sugandha, Monkman, James, Toh, Alan Kie Leong, Hiriyur Nagaraj, Shivashankar , & Thompson, Rik (2017) Targeting epithelial-mesenchymal plasticity in cancer: clinical and preclinical advances in therapy and monitoring. Biochemical Journal, 474(19), pp. 3269-3306.
- 30 citations on Web of Science
28 citations on Scopus
Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: Oncogenic rather than tumor-suppressive role of E-cadherin
Hugo, Honor, Gunasinghe, N.P.A. Devika, Hollier, Brett, Tanaka, T., Blick, Tony, Toh, Alan Kie Leong, Hill, P., Gilles, Christine, Waltham, Mark, & Thompson, Rik (2017) Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin. Breast Cancer Research, 19, Article number: 86 1-25.
- 13 citations on Web of Science
- 15 citations on Scopus
Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer
Skalamera, Duka, Dahmer-Heath, Mareike, Stevenson, Alexander, Pinto, Cletus, Shah, Esha, Daignault, Sheena, Said, Nur Akmarina, Davis, Melissa, Haass, Nikolas, Williams, Elizabeth, Hollier, Brett , Thompson, Rik, Gabrielli, Brian, & Gonda, Thomas (2016) Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer. OncoTarget, 7(38), pp. 61000-61020.
- 5 citations on Web of Science
- 4 citations on Scopus
Tissue factor induced by epithelial-mesenchymal transition triggers a procoagulant state that drives metastasis of circulating tumor cells
Bourcy, Morgane, Suarez-Carmona, Meggy, Lambert, Justine, Francart, Marie-Emilie, Schroeder, Helene, Delierneux, Celine, Skrypek, Nicolas, Thompson, Rik, Jerusalem, Guy, Berx, Geert, Thiry, Marc, Blacher, Silvia, Hollier, Brett, Noel, Agnes, Oury, Cecile, Polette, Myriam, & Gilles, Christine (2016) Tissue factor induced by epithelial-mesenchymal transition triggers a procoagulant state that drives metastasis of circulating tumor cells. Cancer Research, 76(14), pp. 4270-4282.
- 30 citations on Web of Science
- 34 citations on Scopus
Altered purinergic receptor-Ca2+ signaling associated with hypoxia-induced epithelial-mesenchymal transition in breast cancer cells
Azimi, Iman, Beilby, Hannah, Davis, Felicity, Marcial, Daneth, Kenny, Paraic, Thompson, Rik, Roberts-Thomson, Sarah, & Monteith, Gregory (2016) Altered purinergic receptor-Ca2+ signaling associated with hypoxia-induced epithelial-mesenchymal transition in breast cancer cells. Molecular Oncology, 10(1), pp. 166-178.
- 39 citations on Web of Science
- 38 citations on Scopus
Increased COX-2 expression in epithelial and stromal cells of high mammographic density tissues and in a xenograft model of mammographic density
Chew, Grace, Huo, Cecilia, Huang, David, Hill, P., Cawson, Jennifer, Frazer, Helen, Hopper, John, Haviv, Izhak, Henderson, Michael, Britt, Kara, & Thompson, Rik (2015) Increased COX-2 expression in epithelial and stromal cells of high mammographic density tissues and in a xenograft model of mammographic density. Breast Cancer Research and Treatment, 153(1), pp. 89-99.
- 8 citations on Web of Science
- 9 citations on Scopus
Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines
Cursons, Joseph, Leuchowius, Karl-Johan, Waltham, Mark, Tomaskovic-Crook, Eva, Foroutan, Momeneh, Bracken, Cameron, Redfern, Andrew, Crampin, Edmund, Street, Ian, Davis, Melissa, & Thompson, Rik (2015) Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines. Cell Communication and Signaling, 13, Article number: 26 1-21.
- 29 citations on Web of Science
- 27 citations on Scopus
A role for calcium in the regulation of ATP-binding cassette, sub-family C, member 3 (ABCC3) gene expression in a model of epidermal growth factor-mediated breast cancer epithelial-mesenchymal transition
Stewart, Teneale, Azimi, Iman, Thompson, Rik, Roberts-Thomson, Sarah, & Monteith, Gregory (2015) A role for calcium in the regulation of ATP-binding cassette, sub-family C, member 3 (ABCC3) gene expression in a model of epidermal growth factor-mediated breast cancer epithelial-mesenchymal transition. Biochemical and Biophysical Research Communications, 458(3), pp. 509-514.
- 16 citations on Web of Science
- 17 citations on Scopus
Clinical implications of circulating tumor cells of breast cancer patients: Role of epithelial-mesenchymal plasticity
McInnes, Linda, Jacobson, Natalie, Redfern, Andrew, Dowling, Anthony, Thompson, Rik, & Saunders, Christobel (2015) Clinical implications of circulating tumor cells of breast cancer patients: role of epithelial-mesenchymal plasticity. Frontiers in Oncology, 5, Article number: 42 1-7.
- 46 citations on Web of Science
- 46 citations on Scopus
Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent
Davis, Felicity, Azimi, I, Faville, RA, Peters, A, Jalink, K, Putney, JW, Goodhill, Geoffrey, Thompson, Erik, Roberts-Thomson, Sarah, & Monteith, Gregory (2014) Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent. Oncogene, 33(18), pp. 2307-2316.
- 159 citations on Web of Science
- 164 citations on Scopus
Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor
Fifis, Theodora, Nguyen, Linh, Malcontenti-Wilson, Cathy, Chan, Lie, Costa, Patricia, Daruwalla, Jurstine, Nikfarjam, Mehrdad, Muralidharan, Vijayaragavan, Waltham, Mark, Thompson, Rik, & Christophi, Christopher (2013) Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor. Cancer Medicine, 2(5), pp. 595-610.
- 9 citations on Web of Science
- 10 citations on Scopus
Assessment of gene expression of intracellular calcium channels, pumps and exchangers with epidermal growth factor-induced epithelial-mesenchymal transition in a breast cancer cell line
Davis, Felicity, Parsonage, Michelle, Cabot, Peter, Parat, Marie-Odile, Thompson, Erik, Roberts-Thomson, Sarah, & Monteith, Gregory (2013) Assessment of gene expression of intracellular calcium channels, pumps and exchangers with epidermal growth factor-induced epithelial-mesenchymal transition in a breast cancer cell line. Cancer Cell International, 13, Article number: 76 1-7.
- 36 citations on Web of Science
- 36 citations on Scopus
Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells
Hugo, Honor, Pereira, Lloyd, Suryadinata, Randy, Drabsch, Yvette, Gonda, Thomas, Gunasinghe, Devika, Pinto, Cletus, Soo, Eliza, van Denderen, Bryce, Hill, Prue, Ramsay, Robert, Sarcevic, Boris, Newgreen, Don, & Thompson, Erik (2013) Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells. Breast Cancer Research, 15, Article number: R113 1-19.
- 42 citations on Web of Science
- 43 citations on Scopus
Progress in epithelial-mesenchymal transition research
Newgreen, Don & Thompson, Erik (2013) Progress in epithelial-mesenchymal transition research [Editorial]. Cells, Tissues, Organs, 197(6), pp. 421-423.
- citations on Web of Science
- citations on Scopus
A dynamic in vivo model of epithelial-to-mesenchymal transitions in circulating tumor cells and metastases of breast cancer
Bonnomet, Arnaud, Syne, L, Brysse, Anne, Feyereisen, E, Thompson, Rik, Noel, A, Foidart, J-M, Birembaut, P, Polette, Myriam, & Gilles, Christine (2012) A dynamic in vivo model of epithelial-to-mesenchymal transitions in circulating tumor cells and metastases of breast cancer. Oncogene, 31(33), pp. 3741-3753.
- 127 citations on Web of Science
- 126 citations on Scopus
Mesenchymal-epithelial transition (MET) as a mechanism for metastatic colonisation in breast cancer
Gunasinghe, Devika, Wells, Alan, Thompson, Rik, & Hugo, Honor (2012) Mesenchymal-epithelial transition (MET) as a mechanism for metastatic colonisation in breast cancer. Cancer and Metastasis Reviews, 31(3-4), pp. 469-478.
- 185 citations on Web of Science
- 193 citations on Scopus
Soiling the seed : microenvironment and epithelial mesenchymal plasticity
Haviv, I & Thompson, Rik (2012) Soiling the seed : microenvironment and epithelial mesenchymal plasticity. Cancer Microenvironment, 5(1), pp. 1-3.
- 5 citations on Web of Science
- 8 citations on Scopus
Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile
Latifi, Ardian, Abubaker, Khalid, Castrechini, Natalie, Ward, Alister, Liongue, Clifford, Dobill, Francoise, Kumar, Janani, Thompson, Erik, Quinn, Michael, Findlay, Jock, & Ahmed, Nuzhat (2011) Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile. Journal of Cellular Biochemistry, 112(10), pp. 2850-2864.
- 157 citations on Web of Science
- 155 citations on Scopus
Defining the E-cadherin repressor interactome in epithelial-mesenchymal transition: The PMC42 model as a case study
Hugo, Honor, Kokkinos, Maria, Blick, Tony, Ackland, Leigh, Thompson, Rik, & Newgreen, Don (2011) Defining the E-Cadherin repressor interactome in epithelial-mesenchymal transition : the PMC42 model as a case study. Cells Tissues Organs, 193(1-2), pp. 23-40.
- 48 citations on Web of Science
- 50 citations on Scopus
Remodeling of purinergic receptor-mediated Ca 2+ signaling as a consequence of EGF-induced epithelial-mesenchymal transition in breast cancer cells
Davis, Felicity, Kenny, Paraic, Soo, Eliza, van Denderen, Bryce, Thompson, Rik, Cabot, Peter, Parat, Marie-Odile, Roberts-Thomson, Sarah, & Monteith, Gregory (2011) Remodeling of Purinergic Receptor-Mediated Ca2+ Signaling as a Consequence of EGF-Induced Epithelial-Mesenchymal Transition in Breast Cancer Cells. PLoS One, 6(8), Article number: e23464 1-9.
- 38 citations on Web of Science
- 38 citations on Scopus
Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44HI/CD24lO/-stem cell phenotype in human breast cancer
Blick, Tony, Hugo, Honor, Widodo, Edwin, Waltham, Mark, Pinto, Cletus, Mani, Sendurai, Weinberg, Robert, Neve, R, Lenburg, M, & Thompson, Rik (2010) Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the CD44(hi/)CD24(lo/-) Stem Cell Phenotype in Human Breast Cancer. Journal of Mammary Gland Biology and Neoplasia, 15(2), pp. 235-252.
- 200 citations on Web of Science
- 207 citations on Scopus
Mammary gland studies as important contributors to the cause of epithelial mesenchymal plasticity in malignancy
Ford, H.L. & Thompson, Rik (2010) Mammary gland studies as important contributors to the cause of epithelial mesenchymal plasticity in malignancy. Journal of Mammary Gland Biology and Neoplasia, 15(2), pp. 113-115.
- 5 citations on Web of Science
- 5 citations on Scopus
Cadherins in the human placenta : epithelial-mesenchymal transition (EMT) and placental development
Kokkinos, Maria, Murthi, P, Wafai, Razan, Thompson, Rik, & Newgreen, Don (2010) Cadherins in the human placenta : epithelial-mesenchymal transition (EMT) and placental development. Placenta, 31(9), pp. 747-755.
95 citations on Web of Science- 101 citations on Scopus
Epithelial-to-mesenchymal transitions and circulating tumor cells
Bonnomet, Arnaud, Brysse, Anne, Tachsidis, Anthony, Waltham, Mark, Thompson, Rik, Polette, Myriam, & Gilles, Christine (2010) Epithelial-to-mesenchymal transitions and circulating tumor cells. Journal of Mammary Gland Biology and Neoplasia, 15(2), pp. 261-273.
- 161 citations on Web of Science
- 172 citations on Scopus
Epithelial to mesenchymal transition and breast cancer
Tomaskovic-Crook, Eva, Thompson, Rik, & Thiery, Paul (2009) Epithelial to mesenchymal transition and breast cancer. Breast Cancer Research, 11(213), pp. 1-10.
- 190 citations on Web of Science
- 208 citations on Scopus
Myogel supports the ex-vivo amplification of corneal epithelial cells
Francis, D, Abberton, Keren, Thompson, Rik, & Daniell, M (2009) Myogel supports the ex-vivo amplification of corneal epithelial cells. Experimental Eye Research, 88(3), pp. 339-346.
- 24 citations on Web of Science
- 25 citations on Scopus
Epithelial mesenchymal transition traits in human breast cancer cell lines
Blick, Tony, Widodo, Edwin, Hugo, Honor, Waltham, Mark, Lenburg, M, Neve, R, & Thompson, Rik (2008) Epithelial mesenchymal transition traits in human breast cancer cell lines. Clinical and Experimental Metastasis, 25(6), pp. 629-642.
- 234 citations on Web of Science
- 240 citations on Scopus
Epithelial-mesenchymal transition
Zavadil, Jiri, Haley, John, Kalluri, Raghu, Muthuswamy, Senthil, & Thompson, Rik (2008) Epithelial-mesenchymal transition. Cancer Research, 68(23), pp. 9574-9577.
- 103 citations on Web of Science
- 108 citations on Scopus
